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gamma-aminobutyric acid receptor subunit beta-1; GABA(A) receptor subunit beta-1 (GABRB1)
Function:
- GABA-A receptor beta subunit
- binds UBQLN1 (putative)
Structure:
- belongs to the ligand-gated ionic channel (TC 1.A.9) family
Compartment: cell junction, synapse, postsynaptic cell membrane
General
gamma-aminobutyric acid (GABA) A receptor, beta
glycoprotein
transmembrane 4e protein
Properties
SIZE: entity length = 474 aa
MW = 54 kD
COMPARTMENT: plasma membrane
MOTIF: exoplasmic domain {1-245}
MOTIF: signal sequence {1-25}
N-glycosylation site {N105}
cysteine residue {C161}
MODIFICATION: cysteine residue {C175}
N-glycosylation site {N174}
cysteine residue {C175}
MODIFICATION: cysteine residue {C161}
transmembrane domain {246-267}
cytoplasmic loop {268-270}
transmembrane domain {271-293}
exoplasmic loop {294-304}
transmembrane domain {305-327}
cytoplasmic loop {328-451}
MOTIF: Ser phosphorylation site {S448}
transmembrane domain {452-473}
exoplasmic domain {473-474}
Database Correlations
OMIM 137190
UniProt P18505
PFAM correlations
Entrez Gene 2560
Kegg hsa:2560
References
- UniProt :accession P18505
- Protein Spotlight; Note: forbidden fruit -
Issue 56 of March 2005
http://www.expasy.org/spotlight/back_issues/sptlt056.shtml