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gamma-aminobutyric acid receptor subunit alpha-6; GABA(A) receptor subunit alpha-6 (GABRA6)
Function:
- GABA-A receptor alpha subunit
- binds UBQLN1 (putative)
Structure:
- belongs to the ligand-gated ionic channel (TC 1.A.9) family
Compartment:
- cell junction, synapse, postsynaptic cell membrane
General
gamma-aminobutyric acid (GABA) A receptor, alpha
glycoprotein
transmembrane 4e protein
Properties
SIZE: entity length = 453 aa
MW = 51 kD
COMPARTMENT: plasma membrane
MOTIF: exoplasmic domain {1-242}
MOTIF: signal sequence {1-19}
N-glycosylation site {N31}
N-glycosylation site {N128}
N-glycosylation site {N141}
cysteine residue {C156}
MODIFICATION: cysteine residue {C170}
cysteine residue {C170}
MODIFICATION: cysteine residue {C156}
transmembrane domain {243-264}
cytoplasmic loop {265-268}
transmembrane domain {269-290}
exoplasmic loop {291-300}
transmembrane domain {301-324}
cytoplasmic loop {325-419}
transmembrane domain {420-441}
exoplasmic domain {442-453}
Database Correlations
OMIM 137143
UniProt Q16445
PFAM correlations
Entrez Gene 2559
Kegg hsa:2559
References
- UniProt :accession Q16445
- Protein Spotlight; Note: forbidden fruit -
Issue56 of March 2005
http://www.expasy.org/spotlight/back_issues/sptlt056.shtml