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gamma-aminobutyric acid receptor subunit alpha-3; GABA(A) receptor subunit alpha-3 (GABRA3)
Function:
- GABA-A receptor alpha subunit
- binds UBQLN1 (putative)
Structure:
- belongs to the ligand-gated ionic channel (TC 1.A.9) family
Compartment:
- cell junction, synapse, postsynaptic cell membrane
General
gamma-aminobutyric acid (GABA) A receptor, alpha
glycoprotein
transmembrane 4e protein
Properties
SIZE: entity length = 492 aa
MW = 55 kD
COMPARTMENT: plasma membrane
MOTIF: exoplasmic domain {1-276}
MOTIF: signal sequence {1-28}
N-glycosylation site {N63}
N-glycosylation site {N163}
N-glycosylation site {N176}
cysteine residue {C191}
MODIFICATION: cysteine residue {C205}
cysteine residue {C205}
MODIFICATION: cysteine residue {C191}
N-glycosylation site {N228}
transmembrane domain {277-298}
cytoplasmic loop {299-303}
transmembrane domain {304-325}
exoplasmic loop {326-337}
transmembrane domain {338-359}
cytoplasmic loop {360-457}
MOTIF: Ser phosphorylation site {S433}
transmembrane domain {458-479}
exoplasmic domain {480-492}
Database Correlations
OMIM 305660
UniProt P34903
PFAM correlations
Entrez Gene 2556
Kegg hsa:2556
References
- UniProt :accession P34903
- Protein Spotlight; Note: forbidden fruit -
Issue 56 of march 2005
http://www.expasy.org/spotlight/back_issues/sptlt056.shtml