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G protein-regulated inducer of neurite outgrowth 1 (GPRIN1, KIAA1893)
Function:
1) neurite outgrowth (putative)
2) interacts with activated forms of GNAI1, GNAO1, GNAZ
Compartment:
- cell membrane; lipid-anchor (palmitate)
- highly enriched in growth cone
Alternative splicing: named isoforms=2
Expression:
- widely expressed in central nervous system highest levels in spinal cord
General
membrane protein
phosphoprotein
Properties
SIZE: MW = 102 kD
entity length = 1008 aa
COMPARTMENT: cellular membrane
MOTIF: Thr phosphorylation site {T877}
GNAO1 interaction {899-1008}
MOTIF: cysteine residue {C999}
MODIFICATION: palmitate
COMPARTMENT: membrane
cysteine residue {C1000}
MODIFICATION: palmitate
COMPARTMENT: membrane
Database Correlations
UniProt Q7Z2K8
References
UniProt :accession Q7Z2K8