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GTP-binding regulatory protein beta

Function: - G-beta & G-gamma chains are required for a) GTPase activity of heterotrimeric G proteins b) replacement of GDP by GTP c) G protein-effector interaction

Related

G-protein guanine nucleotide-binding protein subunit beta-2-like 1; guanine nucleotide-binding protein subunit beta-like protein 12.3; receptor of activated protein kinase C 1; RACK1; receptor for activated C kinase; cell proliferation-inducing gene 21 protein; Human lung cancer oncogene 7 protein; HLC-7 (GNB2L1)

Specific

GTP-binding regulatory protein beta-1; transducin beta chain 1 (GNB1) GTP-binding regulatory protein beta-2; transducin beta chain 2; (GNB2) GTP-binding regulatory protein beta-3; transducin beta chain 3 (GNB3) GTP-binding regulatory protein beta-4; transducin beta-4 (GNB4) GTP-binding regulatory protein beta-5; transducin beta-5 (GNB5)

General

protein subunit WD repeat protein family

Properties

SIZE: MW = 37 kD entity length = 340 aa MOTIF: WD repeat (8) membrane region Ser phosphorylation site

References

  1. Simon et al, Diversity of G proteins in signal transduction. Science 252:802 1991 PMID: 1902986
  2. Hepler JR & Gilman AG G proteins TIBS 17:383 1992 PMID: 1455506

Component-of

G-beta/gamma