G-protein

Function: - second messengers relaying signals from G-protein-coupled receptors (serpentine receptors) Structure: - G-alpha - ( - GDP/GTP complex

Specific

Gg-protein Gi-protein Gk-protein Go protein Golf-protein Gq-protein Gs-protein (G-stimulatory-protein) Gt-protein or transducin Gz-protein

General

guanine nucleotide regulatory protein (GNRP) multisubunit protein plasma membrane protein

Properties

COMPARTMENT: plasma membrane* CELL: most cell types* ORGANISM: eukaryote* MOTIF: Mg+2-binding site SUBUNITS: G-alpha MOTIF: binding site EFFECTOR-BOUND: G-beta/gamma P-loop EFFECTOR-BOUND: guanosine triphosphate Mg+2-binding site guanine nucleotide-binding site EFFECTOR-BOUND: guanosine diphosphate GTP-binding regulatory protein beta MOTIF: WD repeat (8) membrane region Ser phosphorylation site guanine nucleotide binding protein (G protein), gamma subunit MOTIF: CaaX motif SITE: C-TERMINUS QUALITIES: AAX-TRUNCATED CARBOXYMETHYLATED EFFECTOR-BOUND: prenyl BOUND-VIA: cysteine residue

References

- Wikipedia: G protein http://en.wikipedia.org/wiki/G_protein

Components

G-alpha GTP-binding regulatory protein beta guanine nucleotide binding protein (G protein), gamma subunit