Search
fumarate
An intermediate metabolite in the citric acid cycle & in the urea cycle.
Biochemistry:
- fumarate is an intermediate metabolit in the citric acid cycle
- it is formed from succinate via succinate dehydrogenase
- enzyme: succinate dehydrogenase
- substrates: succinate + flavin adenine dinucleotide
- products: fumarate + FADH2
- it is metabolized to malate via fumarase
- enzyme: fumarase
- substrates: fumarate + H2O
- product: malate
* see citric acid cycle for role of fumarate in citric acid cycle
Interactions
molecular events
Related
citric acid cycle, Krebs cycle or tricarboxylic acid [TCA] cycle
urea cycle
General
alkene; olefin
dicarboxylate
Properties
Database Correlations
PUBCHEM correlations
Component-of
acetaminophen/clemastine/fumarate/pseudoephedrine
bisoprolol/fumarate/hydrochlorothiazide
formoterol/fumarate/mometasone