frontotemporal dementia with parkinsonism (FTDP-17); multiple system tauopathy with presenile dementia (MSTD)

Associated mutations in tau tended to reduce ability of tau to bind microtubules & promote microtubule assembly.

Related

disinhibition-dementia-parkinsonism-amyotrophy complex (DDPAC) parkinsonism

General

frontotemporal dementia; frontotemporal lobar degeneration; frontotemporal neurocognitive disorder (FTD, FTLD) genetic disease of the central nervous system parkinson plus syndrome

Database Correlations

OMIM correlations MORBIDMAP 157140

References

Hong et al. Science 282:1914-7, 1998