flavoprotein mixed function oxidase; flavoprotein monooxygenase; dimethylaniline oxidase; dimethylaniline monooxygenase [N-oxide forming] (FMO)

Flavoprotein in the endoplasmic reticulum that provides oxidizing equivalents for disulfide bond formation, in the maturation (post-translational processing) of secreted & plasma membrane proteins. It also inadvertantly metabolizes xenobiotics.

Specific

flavoprotein monooxygenase 1; dimethylaniline oxidase 1; dimethylaniline monooxygenase [N-oxide forming] (FMO1) flavoprotein monooxygenase 2; dimethylaniline oxidase 2; dimethylaniline monooxygenase (N-oxide forming) 2; pulmonary flavin-containing monooxygenase 2 (FMO2, FMO1B1) flavoprotein monooxygenase 3; dimethylaniline oxidase 3; dimethylaniline monooxygenase (N-oxide forming) 3 (FMO3) flavoprotein monooxygenase 4; dimethylaniline oxidase 4; dimethylaniline monooxygenase [N-oxide forming] 4 (FMO4) flavoprotein monooxygenase 5; dimethylaniline monooxygenase 5 [N-oxide forming]; hepatic flavin-containing monooxygenase 5 (FMO5) flavoprotein monooxygenase 6; dimethylaniline monooxygenase [N-oxide forming] 6; hepatic flavin-containing monooxygenase 6 (FMO6, FMO6P)

General

flavoprotein hydroxylase; monooxygenase

Properties

COMPARTMENT: endoplasmic reticulum MOTIF: active site