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Flash radiotherapy

Indications: - investigational treatment of bone metastases Procedure: - radiation delivered at ultra-high dose rates >= 40 Gray (Gy)/second - can be delivered at 1000 times the dose rate of conventional-dose-rate photon radiotherapy for its potential normal tissue-sparing effects

General

proton therapy

References

  1. Mascia AE, Daugherty EC, Zhang Y et al Proton FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases. The FAST-01 Nonrandomized Trial. JAMA Oncol. Published online October 23, 2022 PMID: 36273324 https://jamanetwork.com/journals/jamaoncology/fullarticle/2797843 - Jarvis LA, Zhang R, Pogue BW The First FLASH Clinical Trial - The Journey of a Thousand Miles Begins With 1 Step. JAMA Oncol. Published online October 23, 2022 PMID: 36273321 https://jamanetwork.com/journals/jamaoncology/fullarticle/2797844
  2. Daugherty EC, Mascia AE, Zhang Y et al FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases (FAST-01): Protocol for the First Prospective Feasibility Study. JMIR Res Protoc. 2022 Oct 4. PMID: 36206189 Free article