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Fitz-Hugh-Curtis syndrome; Gonococcal/Chlamydia perihepatitis

Etiology: - complication of pelvic inflammatory disease - Chlamydia trachomatis - Neisseria gonorrhoeae Epidemiology: - rare - occurs almost exclusively in women Pathology: - peritonitis - perihepatitis Clinical manifestations: - fever, chills, headaches, malaise - right upper quadrant abdominal pain - pelvic adnexal tenderness Laboratory: - complete blood count (CBC): leukocytosis - Chlamydia trachomatis DNA - Neisseria gonorrhoeae DNA - liver function tests generally unchanged from baseline Special laboratory: - cervical smear showing Neisseria gonorrhoeae Radiology: - abdominal ultrasound generally normal Complications: - abdominal adhesions Management: - treat underlying infection - ceftriaxone plus azithromycin - doxycycline, oflaxacin, metronidazole - laparoscopy for lysis of adhesions

General

syndrome

References

  1. Fitz Hugh Curtis Syndrome National Organization for Rare Disorders (NORD) https://rarediseases.org/rare-diseases/fitz-hugh-curtis-syndrome/
  2. Wikipedia: Fitz-Hugh-Curtis syndrome https://en.wikipedia.org/wiki/Fitz-Hugh%E2%80%93Curtis_syndrome
  3. Medical Knowledge Self Assessment Program (MKSAP) 19 Board Basics. An Enhancement to MKSAP19. American College of Physicians, Philadelphia 2022