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azelaic acid (Azelex, Finacea, Finevin)
Indications:
- topical agent for adjuctive treatment of:
a) acne
b) rosacea
Contraindications:
pregnancy category: B
safety in lactation: ?
Dosage:
- apply BID.
Finevin, Azelex: 20%
Finacea Gel 15% less acidic than Finevin, Azelex
Adverse effects:
- local irritation [3]
Mechanism of action:
1) tyrosinase inhibitor
2) cytotoxic to melanocytes [2]
General
dermatologic agent
Database Correlations
PUBCHEM cid=2266
References
- Prescriber's Letter 10(4):22 2003
- Goodheart HP & Mamis S
Skin disorders in women of color
Disorders of pigmentation - melasma
Women's Health in Primary Care 8:473, 2005
- Medical Knowledge Self Assessment Program (MKSAP) 17,
American College of Physicians, Philadelphia 2015
Component-of
azelaic acid/folic acid/nicotinamide/pyridoxine/zinc oxide