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filovirus
Pathology:
- receptor tyrosine kinases AXL & MERTK may function as a cell entry factors
Genetics:
- filamentous, enveloped particles with a negative-sense, single-stranded RNA genome, approximately 19 kb long [1]
Laboratory:
- filovirus antibody in serum
Specific
ebola virus
Marburg virus
General
filoviridae
Properties
KINGDOM: virus
GENOME-TYPE: RNA
SINGLE-STRANDED
NEGATIVE-STRAND
GENOME-SIZE: 13 kB
ENVELOPE: PRESENT
CAPSID-SYMMETRY: HELICAL
References
- Feldmann H, Klenk HD
Chapter 72: Filoviruses
Medical Microbiology. 4th edition.
NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK8129/
- Loinc