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Fidgetin-like protein 1 (FIGNL1)
Function:
- may regulate osteoblast proliferation & differentiation
- phosphorylated upon DNA damage, probably by ATM or ATR
ATP + H2O ADP + phosphate
Cofactor: Mg+2 (putative)
Structure:
- belongs to the AAA ATPase family
- hexamer (putative)
Alternative splicing: named isoforms=2
General
adenosine triphosphatase (ATPase)
phosphoprotein
Properties
SIZE: entity length = 674 aa
MW = 74 kD
MOTIF: Ser phosphorylation site {S157}
active site
MOTIF: adenine nucleotide-binding site
ATP-binding site
NAME: ATP-binding site
SITE: 441-448
Database Correlations
UniProt Q6PIW4
PFAM correlations
References
UniProt :accession Q6PIW4