familial nonchromaffin paraganglioma

Genetics: - autosomal dominant non-chromaffin paraganglioma type 1 associated with defects in SDHD (penetrance is incomplete when transmitted through fathers; not transmitted maternally) - autosomal dominant non-chromaffin paraganglioma type 3 associated with defect in SDHC

Specific

familial nonchromaffin paraganglioma 1 (PGL1) familial nonchromaffin paraganglioma 3 (PGL3) familial nonchromaffin paraganglioma 4 (PGL4)

General

hereditary neoplastic syndrome; cancer susceptibility syndrome paraganglioma

Database Correlations

OMIM correlations MORBIDMAP 602690

References

Baysal et al. Science 287:848-51, 2000