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familial hemiplegic migraine type 3 (FHM3)

Genetics: - autosomal dominant - associated with defects in SCN1A Clinical manifestations: - severe subtype of migraine with aura & some degree of hemiparesis during the attacks - variable features of nausea, vomiting, photophobia, & phonophobia - age at onset ranges from 6 to 15 years - occasionally associated with other neurologic symptoms, such as cerebellar ataxia or epileptic seizures - a unique eye phenotype of elicited repetitive daily blindness has also been reported to be cosegregating with FHM3 in a single Swiss family

General

familial migraine syndrome

Database Correlations

OMIM 609634

References

OMIM :accession 609634