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failure to thrive

In pediatrics: - infant's weight gain & growth far below expected for age In geriatrics: - an unexplained decrease in function, structure or metabolic process in excess of the expected for an age-matched cohort Etiology: 1) organic 2) non-organic 3) often a precipitating event Clinical manifestations: 1) weight loss 2) sarcopenia 3) physical frailty 4) decubitus ulcers Laboratory: 1) serum cholesterol: hypocholesterolemia 2) serum albumin: hypoalbuminemia 3) complete blood count (CBC): anemia of chronic disease Differential diagnosis: 1) organic causes - cancer - organ failure - heart - liver - kidney - chronic infection - endocrine disorders 2) non-organic (psychologic) - depression - dementia - psychosis - grief - suicidal ideation 3) functional problems - immobility - arthritis - deafness - blindness - dental problems 4) neglect or abuse - caregiver burnout - elder abuse Management: 1) identify precipitating event 2) multidisciplinary approach 3) treat identifyable treatable causes 4) refer to social work or Adult Protective Services if indicated 5) respite care for burned-out caregiver

General

sign/symptom syndrome failure

References

  1. Stedman's Medical Dictionary 27th ed. Lippincot, Williams & Wilkins
  2. Verdery RB, Clinics in Geriatric Medicine 11(4):653 1995