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Factor Ix Parenteral

Indications: - to control bleeding in patients with factor IX deficiency (hemophilia B or Christmas disease) Structure: - modified factor IX (rFIXFc) incorporates an immunoglobulin Fc fragment that prolongs its half-life in the blood [1]

General

coagulation factor IX; Christmas factor; plasma thromboplastin component; PTC; contains: coagulation factor IXa light chain; coagulation factor IXa heavy chain (F9) parenteral agent

References

  1. Powell JS et al Phase 3 Study of Recombinant Factor IX Fc Fusion Protein in Hemophilia B. N Engl J Med. Dec 4, 2013 PMID: 24304002 http://www.nejm.org/doi/full/10.1056/NEJMoa1305074