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extended-release (ER)

denoting an oral medication that release slowly over an extended perior of time, similar to sustained action (SA), in contrast to immediate-release. Notes: - some generics are not equivalent to the brand name counterparts in terms of extended release of active ingredient [1,2,3]

References

  1. Thomas K An Increase in Scrutiny for Generics New York Times, Oct 31, 2012 http://www.nytimes.com/2012/11/01/business/fda-increases-scrutiny-of-some-generic-drugs.html
  2. FDA Update: October 3, 2012 Budeprion XL 300 mg Not Therapeutically Equivalent to Wellbutrin XL 300 mg http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm322161.htm
  3. Orciari Herman A FDA Planning Study of Generic Metoprolol Over Safety, Efficacy Concerns. NEJM Journal Watch. May 9, 2014 Massachusetts Medical Society (subscription needed) http://www.jwatch.org