exosome complex exonuclease MTR3 (mRNA transport regulator 3 homolog, hMtr3, exosome component 6, p11, EXOSC6 MTR3)

Function: - component of the exosome multienzyme ribonuclease complex - required for the 3' processing of the 7S pre-RNA to the mature 5.8S rRNA - probably has a 3'-5' exonuclease activity - in the exosome, interacts directly with EXOSC1,EXOSC7 & EXOSC8 Structure: belongs to the RNase PH family Compartment: cytoplasm, nucleus, nucleolus

Properties

SIZE: MW = 28 kD entity length = 272 aa COMPARTMENT: cytoplasm cell nucleus MOTIF: active site

Database Correlations

OMIM 606490 UniProt Q5RKV6 Pfam PF01138 ENZYME 3.1.13.-

References

UniProt :accession Q5RKV6