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roseola (exanthem subitum, 6th disease)
Etiology:
- human herpesvirus type-6
- human herpesvirus type-7
Epidemiology:
- generally affects children < 3 years of age
- oral shedding probable route of disease transmission [3]
Pathology:
- may persist chronically in salivary gland tissue in some hosts [3]
Clinical manifestations:
1) fever
- high, spiking fevers lasting 3-7 days in an otherwise well-appearing child [2]
2) diffuse maculopapular rash (sparing face) appears after resolution of fever [2]
3) rash resolves within 2 days
* images [3]
Related
Dukes disease (4th disease)
erythema infectiosum (5th disease)
Herpes virus infection
measles (1st disease)
rubella (German measles, 3rd disease)
scarlet fever (2nd disease)
General
viral infection
childhood exanthem (numbered diseases)
References
- Harrison's Principles of Internal Medicine, 14th ed.
Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 91
- NEJM Knowledge+ May 12, 2015
- Brady MP (images)
Cutaneous and Mucosal Manifestations of Viral Diseases.
Medscape. March 2017
http://reference.medscape.com/features/slideshow/viral-skin