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estetrol (E4)
- naturally occuring, plant-based estrogen
- also produced by the fetal liver
- less potent than other estrogens
- may reduce vasomotor symptoms of menopause (not FDA-approved)
Interactions
drug adverse effects of estrogens
General
estrogen
References
- Putka S
Novel Plant-Based Estrogen Cuts Menopause Symptoms.
E4Comfort II trial also found improvements in quality of life and markers
of bone health.
MedPage Today September 17, 2024
https://www.medpagetoday.com/meetingcoverage/tms/111988