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erythropoietin in serum
Reference interval:
- 4-27 mU/mL [4], 5-36 mU/mL [1]
- < 19 mU/mL [3]
Indications:
- evaluation of hypoplastic anemia
Contraindications:
- routine measurement of serum erythropoietin in patients with chronic kidney disease*
* not useful for determinining eleigibility for erythropoiesis-stimulating agent [3]
Increases:
1) pure red cell aplasia
2) iron deficiency anemia
3) autonomous production
- renal cell carcinoma [3,4]
- hepatocellular carcinoma [3]
- pheochromocytoma [3]
4) erythrocytosis (secondary polycythemia)
5) anabolic steroids
Decreases:
1) chronic renal failure
2) polycythemia rubra vera
3) rheumatoid arthritis
4) human immune deficiency virus (HIV) infection
- zidovudine can increase erythropoietin levels
6) amphotericin B
serum levels are low, but not absent
Related
erythropoietin (EPO)
polycythemia
General
special chemistry test
References
- Clinical Guide to Laboratory Tests, 3rd edition, NW Tietz
ed, WB Saunders, Philadelphia, 1995
- Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed)
Lippincott-Raven, Philadelphia, 1998, pg 412-13
- Medical Knowledge Self Assessment Program (MKSAP) 11, 16, 17
American College of Physicians, Philadelphia 1998, 2012, 2015
- Erythropoietin
Laboratory Test Directory ARUP: 50227