epithelial-stromal interaction protein 1 (EPSTI1)

Alternative splicing: named isoforms=3 Note: variant in position: 338:P->S (in dbSNP:rs11557739) variant in position: 399:N->K (in dbSNP:rs1044856) Expression: - highly expressed in placenta, small intestine, spleen, kidney, thymus, liver, salivary gland & testes. - weakly expressed in breast, skeletal muscle & colon Pathology: - highly expressed in breast cancer upon interaction between tumor cells & stromal cells in vitro - expressed in blood mononuclear cells from patients with systemic lupus erythematosus (SLE) - up-regulated in breast carcinomas

Properties

SIZE: entity length = 318 aa MW = 37 kD MOTIF: coiled coil {73-188} coiled coil {240-280}

References

UniProt :accession Q96J88