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eosinophilic gastritis
Etiology:
- idiopathic, possibly allergic
- generally occurs in atopic persons (suggested by eosinophilia)
Epidemiology: rare
Pathology:
- infiltration of eosinophils into the stomach
- small intestine may be involved
Special laboratory:
- upper GI endoscopy
- gastric mucosa may appear normal
- gastric biology
- eosinophils in gastric mucosa > 10/HPF
- allergy testing to identify foods to eliminate
Differential diagnosis:
- drugs
- parasitic infections
- bacterial infections
- inflammatory bowel disease
- Crohn's disease
- vasculitis
- polyarteritis
- allergic vasculitis
- hypereosinophilic syndrome
- connective tissue disease
- scleroderma
- myeloproliferative disorders
Management:
- food elimination (see eosinophilic esophagitis)
- glucocorticoids vs elemental diet if food elimination fails
General
gastritis
References
- Medical Knowledge Self Assessment Program (MKSAP) 18,
American College of Physicians, Philadelphia 2018
- Medical Knowledge Self Assessment Program (MKSAP) 20
American College of Physicians, Philadelphia 2025