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enzyme

A protein catalyst in an enzymatic reaction. The active site of the enzyme facilitates the catalysis. Since an enzyme is a catalyst, it is unchanged by the enzymatic reaction it catalyzes.

Interactions

molecular events

Specific

3-phosphoinositide-dependent protein kinase 2 (PDPK2) allosteric enzyme aspartate aminotransferase, cytoplasmic 2 (transaminase A-like protein 1, glutamate oxaloacetate transaminase 1-like protein 1, GOT1L1) bacteriophage lysin beta-galactosidase-1-like protein 2 (GLB1L2) bifunctional protein NCOAT; meningioma-expressed antigen 5; nuclear cytoplasmic O-GlcNAcase & acetyltransferase; includes: protein O-GlcNAcase; glycoside hydrolase O-GlcNAcase; hexosaminidase C; N-acetyl-beta-D-glucosaminidase; N-acetyl-beta-glucosaminidase; O-GlcNAcase; OGA; includes: histone acetyltransferase; HAT (MGEA5, HEXC, KIAA0679, MEA5) cation-transporting ATPase 13A4 (P5-ATPase isoform 4, ATP13A4) chromodomain-helicase-DNA-binding protein 1-like (amplified in liver cancer protein 1, CHD1L, ALC1) citric acid cycle enzyme CTD small phosphatase-like protein 2 (CTDSP-like 2, CTDSPL2) cylicin-2 (multiple-band polypeptide 2, CYLC2, CYL2) cytosolic purine 5'-nucleotidase (5'-nucleotidase cytosolic 2, NT5C2, NT5B, NT5CP, PNT5) dehydrodolichyl diphosphate synthase (Dedol-PP synthase, DHDDS, HDS) demethylase electron transport enzyme exonuclease domain-containing protein 1 (EXOD1, KIAA1504, ERI2) fatty acid 2-hydroxylase (fatty acid alpha-hydroxylase, FA2H, FAAH) fatty acid desaturase 6 (FADS6) formimidoyltransferase-cyclodeaminase (formiminotransferase-cyclodeaminase, FTCD, LCHC1 [includes: glutamate formimidoyltransferase/glutamate formiminotransferase/glutamate formyltransferase & formimidoyltetrahydrofolate cyclodeaminase/formiminotetrahydrofolate cyclodeaminase]) gamma-glutamyltranspeptidase 3 (gamma-glutamyltransferase 3) [contains: gamma-glutamyltranspeptidase 3 heavy chain; gamma-glutamyltranspeptidase 3 light chain] (GGT3P GGT3) genetically-modified enzyme gluconeogenic enzyme glycerol-3-phosphate dehydrogenase 1-like protein (GPD1L, KIAA0089) glycolytic enzyme glyoxylate reductase/hydroxypyruvate reductasel D-glycerate dehydrogenase; D-glyceric dehydrogenase (GRHPR, GLXR, MSTP035) guanine nucleotide exchange factor (GDP/GTP dissociation stimulator, guanine nucleotide-releasing factor/protein, GNEF, GNDS, GDS) holoenzyme hydrolase isomerase kynurenine-oxoglutarate transaminase 1 (kynurenine aminotransferase 1, KATI, glutamine-phenylpyruvate transaminase, glutamine transaminase K, GTK, cysteine-S-conjugate beta-lyase, CCBL1) ligase or synthetase lipid phosphate phosphatase-related protein type 5 (plasticity-related gene 5 protein, PRG-5, phosphatidic acid phosphatase 2d) (LPPR5 PAP2D) lyase malate dehydrogenase 1B (MDH1B) metallophosphoesterase FLJ45032 (TMPPE) mitochondrial inner membrane protease ATP23 homolog (XRCC6-binding protein 1, Ku70-binding protein 3, XRCC6BP1, KUB3) multienzyme complex multifunctional enzyme N-acetylglutamate synthase, mitochondrial (amino-acid acetyltransferase, [Contains: N-acetylglutamate synthase long form; N-acetylglutamate synthase short form; N-acetylglutamate synthase conserved domain form], NAGS) N-acetylneuraminate lyase (NALase, N-acetylneuraminic acid aldolase, N-acetylneuraminate pyruvate-lyase, sialic acid lyase, sialate lyase, sialate-pyruvate lyase, sialic acid aldolase, NPL) N-acetyltransferase MAK3 homologl N-acetyltransferase 12 (NAT12, C14orf35, MAK3, NAA30) nitrilase homolog 2 (NIT2) oxidoreductase permease peroxidasin homolog (vascular peroxidase, melanoma-associated antigen MG50, p53-responsive gene 2 protein) (PXDN KIAA0230 MG50 PRG2 VPO) peroxidasin-like protein (vascular peroxidase 2, cardiac peroxidase, PXDNL, VPO2) peroxisomal 2,4-dienoyl-CoA reductase (2,4-dienoyl-CoA reductase 2, pDCR, DECR2, PDCR) peroxisomal N1-acetyl-spermine/spermidine oxidase (polyamine oxidase, PAOX, PAO, UNQ1923/PRO4398) peroxisomal trans-2-enoyl-CoA reductase (TERP; HPDHase; pVI-ARL; 2,4-dienoyl-CoA reductase-related protein; DCR-RP; PECR) poly(A) RNA polymerase GLD2 (hGLD-2, PAP-associated domain-containing protein 4, PAPD4, GLD2) probable E3 ubiquitin-protein ligase KIAA0614 (KIAA0614, HECTD4) protein notum homolog (NOTUM) serine/threonine protein kinase DCAMKL3; doublecortin-like & CAM kinase-like 3 (DCAMKL3, KIAA1765, DCLK3) serine/threonine protein kinase Nek10 (NimA-related protein kinase 10, NEK10) single-strand selective monofunctional uracil DNA glycosylase sugar kinase FLJ10986 (FGGY) synthase threonyl-tRNA synthetase 2, cytoplasmic (threonine-tRNA ligase, ThrRS, threonyl-tRNA synthetase-like protein 2, TARSL2) transferase UDP-N-acetylhexosamine pyrophosphorylase (antigen X, AGX, sperm-associated antigen 2, [Includes: UDP-N-acetylgalactosamine pyrophosphorylase (AGX-1); UDP-N-acetylglucosamine pyrophosphorylase (AGX-2)], UAP1 SPAG2) UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 (UAP1L1, UAP1) UMP-CMP kinase 2, mitochondrial (CMPK2) urea cycle enzyme Valyl-tRNA synthetase, mitochondrial (valine-tRNA ligase, ValRS, valyl-tRNA synthetase-like, VARS2, KIAA1885 VARS2L VARSL) zinc-binding alcohol dehydrogenase domain-containing protein 2 (ZADH2)

General

protein

Properties

MOTIF: active site

References

Stedman's Medical Dictionary 27th ed, Williams & Wilkins, Baltimore, 1999.