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enzyme
A protein catalyst in an enzymatic reaction. The active site of the enzyme facilitates the catalysis. Since an enzyme is a catalyst, it is unchanged by the enzymatic reaction it catalyzes.
Interactions
molecular events
Specific
3-phosphoinositide-dependent protein kinase 2 (PDPK2)
allosteric enzyme
aspartate aminotransferase, cytoplasmic 2 (transaminase A-like protein 1, glutamate oxaloacetate transaminase 1-like protein 1, GOT1L1)
bacteriophage lysin
beta-galactosidase-1-like protein 2 (GLB1L2)
bifunctional protein NCOAT; meningioma-expressed antigen 5; nuclear cytoplasmic O-GlcNAcase & acetyltransferase; includes: protein O-GlcNAcase; glycoside hydrolase O-GlcNAcase; hexosaminidase C; N-acetyl-beta-D-glucosaminidase; N-acetyl-beta-glucosaminidase; O-GlcNAcase; OGA; includes: histone acetyltransferase; HAT (MGEA5, HEXC, KIAA0679, MEA5)
cation-transporting ATPase 13A4 (P5-ATPase isoform 4, ATP13A4)
chromodomain-helicase-DNA-binding protein 1-like (amplified in liver cancer protein 1, CHD1L, ALC1)
citric acid cycle enzyme
CTD small phosphatase-like protein 2 (CTDSP-like 2, CTDSPL2)
cylicin-2 (multiple-band polypeptide 2, CYLC2, CYL2)
cytosolic purine 5'-nucleotidase (5'-nucleotidase cytosolic 2, NT5C2, NT5B, NT5CP, PNT5)
dehydrodolichyl diphosphate synthase (Dedol-PP synthase, DHDDS, HDS)
demethylase
electron transport enzyme
exonuclease domain-containing protein 1 (EXOD1, KIAA1504, ERI2)
fatty acid 2-hydroxylase (fatty acid alpha-hydroxylase, FA2H, FAAH)
fatty acid desaturase 6 (FADS6)
formimidoyltransferase-cyclodeaminase (formiminotransferase-cyclodeaminase, FTCD, LCHC1 [includes: glutamate formimidoyltransferase/glutamate formiminotransferase/glutamate formyltransferase & formimidoyltetrahydrofolate cyclodeaminase/formiminotetrahydrofolate cyclodeaminase])
gamma-glutamyltranspeptidase 3 (gamma-glutamyltransferase 3) [contains: gamma-glutamyltranspeptidase 3 heavy chain; gamma-glutamyltranspeptidase 3 light chain] (GGT3P GGT3)
genetically-modified enzyme
gluconeogenic enzyme
glycerol-3-phosphate dehydrogenase 1-like protein (GPD1L, KIAA0089)
glycolytic enzyme
glyoxylate reductase/hydroxypyruvate reductasel D-glycerate dehydrogenase; D-glyceric dehydrogenase (GRHPR, GLXR, MSTP035)
guanine nucleotide exchange factor (GDP/GTP dissociation stimulator, guanine nucleotide-releasing factor/protein, GNEF, GNDS, GDS)
holoenzyme
hydrolase
isomerase
kynurenine-oxoglutarate transaminase 1 (kynurenine aminotransferase 1, KATI, glutamine-phenylpyruvate transaminase, glutamine transaminase K, GTK, cysteine-S-conjugate beta-lyase, CCBL1)
ligase or synthetase
lipid phosphate phosphatase-related protein type 5 (plasticity-related gene 5 protein, PRG-5, phosphatidic acid phosphatase 2d) (LPPR5 PAP2D)
lyase
malate dehydrogenase 1B (MDH1B)
metallophosphoesterase FLJ45032 (TMPPE)
mitochondrial inner membrane protease ATP23 homolog (XRCC6-binding protein 1, Ku70-binding protein 3, XRCC6BP1, KUB3)
multienzyme complex
multifunctional enzyme
N-acetylglutamate synthase, mitochondrial (amino-acid acetyltransferase, [Contains: N-acetylglutamate synthase long form; N-acetylglutamate synthase short form; N-acetylglutamate synthase conserved domain form], NAGS)
N-acetylneuraminate lyase (NALase, N-acetylneuraminic acid aldolase, N-acetylneuraminate pyruvate-lyase, sialic acid lyase, sialate lyase, sialate-pyruvate lyase, sialic acid aldolase, NPL)
N-acetyltransferase MAK3 homologl N-acetyltransferase 12 (NAT12, C14orf35, MAK3, NAA30)
nitrilase homolog 2 (NIT2)
oxidoreductase
permease
peroxidasin homolog (vascular peroxidase, melanoma-associated antigen MG50, p53-responsive gene 2 protein) (PXDN KIAA0230 MG50 PRG2 VPO)
peroxidasin-like protein (vascular peroxidase 2, cardiac peroxidase, PXDNL, VPO2)
peroxisomal 2,4-dienoyl-CoA reductase (2,4-dienoyl-CoA reductase 2, pDCR, DECR2, PDCR)
peroxisomal N1-acetyl-spermine/spermidine oxidase (polyamine oxidase, PAOX, PAO, UNQ1923/PRO4398)
peroxisomal trans-2-enoyl-CoA reductase (TERP; HPDHase; pVI-ARL; 2,4-dienoyl-CoA reductase-related protein; DCR-RP; PECR)
poly(A) RNA polymerase GLD2 (hGLD-2, PAP-associated domain-containing protein 4, PAPD4, GLD2)
probable E3 ubiquitin-protein ligase KIAA0614 (KIAA0614, HECTD4)
protein notum homolog (NOTUM)
serine/threonine protein kinase DCAMKL3; doublecortin-like & CAM kinase-like 3 (DCAMKL3, KIAA1765, DCLK3)
serine/threonine protein kinase Nek10 (NimA-related protein kinase 10, NEK10)
single-strand selective monofunctional uracil DNA glycosylase
sugar kinase FLJ10986 (FGGY)
synthase
threonyl-tRNA synthetase 2, cytoplasmic (threonine-tRNA ligase, ThrRS, threonyl-tRNA synthetase-like protein 2, TARSL2)
transferase
UDP-N-acetylhexosamine pyrophosphorylase (antigen X, AGX, sperm-associated antigen 2, [Includes: UDP-N-acetylgalactosamine pyrophosphorylase (AGX-1); UDP-N-acetylglucosamine pyrophosphorylase (AGX-2)], UAP1 SPAG2)
UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 (UAP1L1, UAP1)
UMP-CMP kinase 2, mitochondrial (CMPK2)
urea cycle enzyme
Valyl-tRNA synthetase, mitochondrial (valine-tRNA ligase, ValRS, valyl-tRNA synthetase-like, VARS2, KIAA1885 VARS2L VARSL)
zinc-binding alcohol dehydrogenase domain-containing protein 2 (ZADH2)
General
protein
Properties
MOTIF: active site
References
Stedman's Medical Dictionary 27th ed, Williams &
Wilkins, Baltimore, 1999.