Search
Enterobacteriaceae
Epidemiology:
- emergence of carbapenem-resistant Enterobacteriaceae
- emergence of multidrug-resistant enterobacteriaceae
Laboratory:
- Enterobacteriaceae carbapenemase-resistant identified by culture
- antibiotic susceptibility testing
- carbapenemase-producing Klebsiella spp. & E coli represent the major carbapenem-resistant Enterobacteriaceae in the USA [2]
- glucose fermenter; cytochrome-oxidase -; catalase +
- Enterobacteriaceae DNA
Management:
1) 3rd generation cephalosporin
2) carbapenem (resistance has emerged)
3) alternative: beta-lactam/beta-lactamase inhibitor
4) discharge home to complete therapy with oral agents in complicated cases [2]
Related
multidrug-resistant gram-negative bacteria; multidrug-resistant enterobacteriaceae (MRE)
Specific
carbapenem-resistant Enterobacteriaceae (CRE)
Citrobacter
Cronobacter
Edwardsiella
Enterobacter
Erwinia
Escherichia
Hafnia
Klebsiella
Morganella
Proteus
Providencia
Salmonella
Serratia
Shigella
Yersinia
General
gram-negative facultatively anaerobic rods
Properties
KINGDOM: monera
DIVISION: SCHIZOMYCETES
References
- Medical Knowledge Self Assessment Program (MKSAP) 15, 18
American College of Physicians, Philadelphia 2009, 2018
- Tamma PD, Conley AT, Cosgrove SE et al.
Association of 30-day mortality with oral step-down vs continued
intravenous therapy in patients hospitalized with Enterobacteriaceae
bacteremia.
JAMA Intern Med 2019 Mar; 179:316-323
PMID: 30667477
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2720756