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endophthalmitis

Inflammation of tissues within the eyeball. Etiology: - eye infection - bacterial most common - endogenous skin flora: Staphylococcus epidermidis - Pseudomonas aeruginosa - fungi - post-operative, generally within 6 weeks of surgery - cataract surgery - eye globe trauma - eye foreign body Clinical manifestations: - decreased visual acuity - red eye, conjunctival injection - pain, photophobia - corneal edema, corneal opacification - hypopyon (pus in anterior chamber) - symptoms of infection in adjacent structures or distant site *image [3] Laboratory: - vitreal cultures - blood cultures if systemic origin likely Management: - immediate referral to ophthalmology for intravitreal antibiotics

General

eye infection (ocular infection)

References

  1. Stedman's Medical Dictionary 27th ed, Williams & Wilkins, Baltimore, 1999
  2. Medical Knowledge Self Assessment Program (MKSAP) 15, American College of Physicians, Philadelphia 2009
  3. Elkston CA, Elkston DM Bacterial Skin Infections: More Than Skin Deep. Medscape. July 19, 2021 https://reference.medscape.com/slideshow/infect-skin-6003449
  4. Eye Wiki: Endophthalmitis https://eyewiki.aao.org/Endophthalmitis
  5. Egan DJ, Jagminas L Endophthalmitis Medscape. June 2, 2018 https://emedicine.medscape.com/article/799431-overview
  6. Wikipedia: Endophthalmitis https://en.wikipedia.org/wiki/Endophthalmitis
  7. Durand ML Endophthalmitis. Clin Microbiol Infect. 2013 Mar;19(3):227-34. PMID: 23438028 PMCID: PMC3638360 Free PMC article
  8. Durand ML Bacterial and Fungal Endophthalmitis. Clin Microbiol Rev. 2017 Jul;30(3):597-613. PMID: 28356323 PMCID: PMC5475221 Free PMC article