Search
homeobox protein EMX1; empty spiracles homolog 1; empty spiracles-like protein 1 (EMX1)
Function:
- transcription factor, which in cooperation with EMX2, acts to generate boundary between the roof & archipallium in the developing brain
- may function in combinations with OTX1/2 to specify cell fates in the developing central nervous system
Structure:
- belongs to the EMX homeobox family
- contains 1 homeobox DNA-binding domain
Compartment: nucleus (probable)
Alternative splicing: named isoforms=2
Expression: cerebral cortex
General
homeobox protein
Properties
SIZE: entity length = 257 aa
MW = 28 kD
COMPARTMENT: cell nucleus
MOTIF: homeodomain
SITE: 159-218
Database Correlations
OMIM 600034
UniProt Q04741
Pfam PF00046
Entrez Gene 2016
Kegg hsa:2016
References
UniProt :accession Q04741