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embryonal rhabdomyosarcoma
Epidemiology: ~60% of childhood cases.
Microscopic pathology:
- small round/spindle shaped undifferentiated cells mixed with variable numbers of round, strap or tadpole shaped eosinophilic rhabdomyoblasts in myxoid stroma
Immunohistochemistry: desmin + muscle actin + myogenin and MyoD1 sensitive and specific markers Botryoid and spindle cell variants have better prognosis; anaplastic variant has poor survival rate.
Interactions
disease interactions
Specific
embryonal rhabdomyosarcoma [RMS1]
General
rhabdomyosarcoma (Sarcoma Botryoides)
Database Correlations
OMIM 268210