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epirubicin; pidorubicin (Ellence)
Tradename: Ellence.
Indications:
- axillary node involvement after resection of breast cancer
- Hodgkin's disease
- diffuse large B-cell lymphoma
- gastric cancer
- osteosarcoma [2]
Adverse effects:
- cardiotoxicity -> heart failure [3]
Mechanism of action:
-> anthracycline cytotoxic agent
-> 4' epimer of doxorubicin
Interactions
drug interactions
drug adverse effects of anthracyclines
General
anthracycline
Properties
INHIBITS: topoisomerase
Database Correlations
PUBCHEM correlations
References
- Kaiser Permanente Northern California Drug Information, 2000
- Deprecated Reference
- Medical Knowledge Self Assessment Program (MKSAP) 17,
American College of Physicians, Philadelphia 2015
Component-of
cyclophosphamide/epirubicin/fluorouracil (CEF, FEC-100)
doxorubicin (Adriamycin, Rubex)