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egg allergy

Laboratory: - peanut IgE Ab in serum (severe egg allergy) Management: - oral immunotherapy with egg-white powder ~30% effective [1] - introducing infants to egg at ages 4-6 months is associated with reduced risk for egg allergy [2] - early introduction of heated egg powder can prevent egg allergy in some high-risk infants [3]

General

food allergy

References

  1. Burks AW et al Oral immunotherapy for treatment of egg allergy in children. N Engl J Med 2012 Jul 19; 367:233. PMID: 22808958
  2. Ierodiakonou D et al Timing of Allergenic Food Introduction to the Infant Diet and Risk of Allergic or Autoimmune DiseaseA Systematic Review and Meta-analysis. JAMA. September 20, 2016 PMID: 27654604 http://jama.jamanetwork.com/article.aspx?articleid=2553447
  3. Natsume O, Kabashima S, Nakazato J et al Two-step egg introduction for prevention of egg allergy in high-risk infants with eczema (PETIT): a randomised, double- blind, placebo-controlled trial. Lancet. Dec 8, 2016 PMID: 27939035 http://thelancet.com/journals/lancet/article/PIIS0140-6736(16)31418-0/fulltext - Roberts G Another step towards prevention of food allergy. Lancet. Dec 8, 2016 PMID: 27939036 http://thelancet.com/journals/lancet/article/PIIS0140-6736(16)31661-0/fulltext