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efinaconazole (Jublia)

Indications: - distal lateral subungual onychomycosis (includes great toenail) Dosage: - once daily for 48 weeks 10% solution Adverse effects: - local site reactions Notes: - complete cure rate 15-18% vs 3% for placebo - mycological cure rate were 53-55%

General

antifungal agent

Database Correlations

PUBCHEM cid=489181

References

  1. Elewski BE et al. Efinaconazole 10% solution in the treatment of toenail onychomycosis: Two phase III multicenter, randomized, double- blind studies. J Am Acad Dermatol 2013 Apr; 68:600 PMID: 23177180
  2. Prescriber's Letter 21(8): 2014 Detail-Document#: 300807 (subscription needed) http://www.prescribersletter.com