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eccrine poroma
Epidemiology:
- middle age
- frequency - ~2/3 sole or side of foot, hands and fingers next in frequency.
- variant: eccrine poromatosis
Microscopic pathology:
- arises in lower portion of epidermis, extends downward, often in anastomosing bands
- uniform cuboidal cells with intercellular bridges
- narrow ductal lumen & occasional cystic spaces in tumor bands
- may be located in epidermis (also hidroacanthoma simplex) or dermis
- cells contain significant amount of glycogen
Differential diagnosis:
- seborrheic keratosis
- basal cell carcinoma
- Bowen's disease (which contains cellular atypia)
General
eccrine neoplasm
References
Elder et al eds. Lever's Histopathology of the Skin.
Lippincott-Raven, 8th ed. 1997