dystroglycan complex (GO:0016011)

A protein complex that includes alpha- and beta-dystroglycan which are alternative products of the same gene; the laminin binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin.

General

plasma membrane part (GO:0044459) protein complex (GO:0043234)

References

gene ontology: GO:0016011 PMID: 16710609 PMID: 15117830