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DYPD enzyme activity
Clinical significance:
- defects in DPYD are the cause of dihydropyrimidine dehydrogenase deficiency
- dihydropyrimidine dehydrogenase plays role in degradation of chemotherapeutic drug 5-fluorouracil
Related
dihydropyrimidine dehydrogenase; DHPDHase; dihydrouracil dehydrogenase; dihydrothymine dehydrogenase (DPD, DPYD)
General
toxicology/drug test
References
- Loinc
- ARUP Consult:
Dihydropyrimidine Dehydrogenase (DPYD), 3 Variants
https://arupconsult.com/ati/dihydropyrimidine-dehydrogenase