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dynamin

Function: - mediates sliding between microtubules [1] & may link ras signalling to clathrin-mediated endocytosis [2]

Specific

dynamin 1 (DNM1, DNM) dynamin 2 (DNM2, DYN2) dynamin 3 (testicular dynamin, T-dynamin, DNM3, KIAA0820)

General

guanosine triphosphatase (GTPase)

Properties

MOTIF: active site guanine nucleotide-binding site

References

  1. Hollenbeck PJ. Cell motility. Dynamin joins the family. Nature. 1990 Sep 20;347(6290):229. 'News & Views' PMID: 2144892
  2. Pawson T. Protein modules and signalling networks. Nature. 1995 Feb 16;373(6515):573-80. Review. PMID: 7531822
  3. Kelly RB. Endocytosis. Ringing necks with dynamin. Nature. 1995 Mar 9;374(6518):116-7. No abstract available. PMID: 7877678 - Takei K, McPherson PS, Schmid SL, De Camilli P. Tubular membrane invaginations coated by dynamin rings are induced by GTP-gamma S in nerve terminals. Nature. 1995 Mar 9;374(6518):186-90. PMID: 7877693 - Hinshaw JE, Schmid SL. Dynamin self-assembles into rings suggesting a mechanism for coated vesicle budding. Nature. 1995 Mar 9;374(6518):190-2. PMID: 7877694

Component-of

dynamin complex