Dutch Randomized Endovascular Aneurysm Management trial (DREAM trial)

Design: - 345 patients with abdominal aortic aneurysm > 5 cm in diameter randomized to endovascular vs open repair primary endpoint: 30 day operative mortality or moderate-severe complication Results: - primary endpoint reached in 24% of open repair vs 18% of endovascular repair patients - procedure related mortality was 4.6% in open repair group vs 1.2% in endovascular repair group - cardiac & pulmonary complications occurred significantly more often after open repair - vascular complications occurred more often after endovascular repair

References

Journal Watch 24(22):165, 2004 Prinssen M, Verhoeven EL, Buth J, Cuypers PW, van Sambeek MR, Balm R, Buskens E, Grobbee DE, Blankensteijn JD; Dutch Randomized Endovascular Aneurysm Management (DREAM)Trial Group. A randomized trial comparing conventional and endovascular repair of abdominal aortic aneurysms. N Engl J Med. 2004 Oct 14;351(16):1607-18. PMID: 15483279