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drusen
Etiology:
- age-related macular degeneration
Pathology:
- small yellow-white spots of variable size seen around macula & posterior pole of the eye on funduscopic examination of patients with age-related macular degeneration.
- drusen are accumulations of protein & lipid, beneath the retinal epithelium & within an elastin-containing structure known as Bruch membrane
- the drusen may coalesce heralding progession of macular degeneration from the non-exudative or dry stage to the exudative stage
- drusen typically do not cause loss of vision [2]
Related
macular degeneration
General
retinal deposit
References
- Medical Knowledge Self Assessment Program (MKSAP) 11, 16, 18.
American College of Physicians, Philadelphia 1998, 2012. 2018
- Geriatric Review Syllabus, 8th edition (GRS8)
Durso SC and Sullivan GN (eds)
American Geriatrics Society, 2013