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D-dopachrome decarboxylase; D-dopachrome tautomerase; phenylpyruvate tautomerase 2 (DDT)
Function:
- tautomerization of D-dopachrome with decarboxylation to yield 5,6-dihydroxyindole
D-dopachrome 5,6-dihydroxyindole + CO2
Structure:
- homotrimer
- belongs to the MIF family
Compartment: cytoplasm (putative)
Related
L-dopachrome tautomerase; DCT; DT; L-dopachrome delta-isomerase; tyrosinase-related protein 2; TRP-2; TRP2 (DCT, TYRP2)
General
carboxy-lyase or decarboxylase
Properties
SIZE: entity length = 118 aa
MW = 13 kD
COMPARTMENT: cytoplasm
MOTIF: active site
Database Correlations
OMIM correlations
UniProt P30046
Pfam PF01187
Entrez Gene 1652
Kegg hsa:1652
ENZYME 4.1.1.84
References
UniProt :accession P40126