DNASCO study

Study characteristics: - 140 men, mean age 57 Groups: 1) low-moderate intensity exercise 2) usual activity Progression of atherosclerosis assessed by carotid artery intimal- medial thickness measured by ultrasonography Results: 1) no difference between groups 2) if statin users ere excluded, exercise group showed significantly less progression of atherosclerosis (0.12 vs 0.20 mm) 3) C-reactive protein levels did not differ between groups

References

Journal Watch 24(15):119, 2004 Rauramaa R, Halonen P, Vaisanen SB, Lakka TA, Schmidt-Trucksass A, Berg A, Penttila IM, Rankinen T, Bouchard C. Effects of aerobic physical exercise on inflammation and atherosclerosis in men: the DNASCO Study: a six-year randomized, controlled trial. Ann Intern Med. 2004 Jun 15;140(12):1007-14. PMID: 15197018