Search
DnaJ homolog subfamily C member 15 (methylation-controlled J protein, MCJ, DNAJC15, DNAJD1, HSD18)
Structure:
- contains 1 J domain
Compartment: membrane
Expression: ubiquitous.
Pathology:
- absent or down-regulated in many advanced cases of ovarian cancer, due to hypermethylation & allelic loss
- loss expression correlates with increased resistance to antineoplastic drugs, including cisplatin
General
DNAJ homolog subfamily C
Properties
SIZE: MW = 16 kD
entity length = 150 aa
MOTIF: transmembrane domain {35-57}
J domain {96-150}
Database Correlations
UniProt Q9Y5T4
Pfam PF00226
References
UniProt :accession Q9Y5T4