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dynein intermediate chain 1, axonemal (DNAI1)

Function: - dynein intermediate chain of respiratory cilia Structure: - belongs to the dynein intermediate chain family - contains 5 WD repeats Pathology: - defects in DNAI1 are the cause of primary ciliary dyskinesia type 1/Kartagener syndrome

Related

dynein

General

dynein intermediate chain phosphoprotein WD repeat protein family

Properties

SIZE: MW = 79 kD entity length = 699 aa MOTIF: Ser phosphorylation site {S131} Ser phosphorylation site {S134} WD repeat {381-421} WD repeat {430-473} WD repeat {538-578} WD repeat {580-620} WD repeat {627-666}

Database Correlations

OMIM correlations UniProt Q9UI46 Pfam PF00400 Kegg hsa:2701

References

  1. UniProt :accession Q9UI46
  2. GeneReviews https://www.genecards.org/cgi-bin/carddisp.pl?gene=DNAI1