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disks large-associated protein 3 (DAP-3, SAP90/PSD-95-associated protein 3, SAPAP3, PSD-95/SAP90-binding protein 3, DLGAP3, DAP3)
Function:
- role in molecular organization of synapses & neuronal cell signaling
- adapter protein linking ion channel to the subsynaptic cytoskeleton (putative)
- may induce enrichment of PSD-95/SAP90 at synaptic membrane
- interacts with DLG4/PSD-95
Compartment:
- cell membrane, cell junction, synapse
- postsynaptic cell membrane, postsynaptic density of neurons
General
phosphoprotein
Properties
SIZE: MW = 106 kD
entity length = 979 aa
MOTIF: Ser phosphorylation site {S58}
histidine-rich region {223-234}
MOTIF: histidine residue (SEVERAL)
Ser phosphorylation site {S396}
Ser phosphorylation site {S406}
Ser phosphorylation site {S409}
Ser phosphorylation site {S412}
Ser phosphorylation site {S416}
Ser phosphorylation site {S502}
Ser phosphorylation site {S932}
Ser phosphorylation site {S967}
Database Correlations
UniProt O95886
Pfam PF03359
References
UniProt :accession O95886