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disinhibition
Etiology:
- dementia, especially Pick's disease
- Kluver-Bucy syndrome
Clinical manifestations:
- alcoholism,
- hyperreligiosity
- inappropriate sexual behavior
- excessive eating
- shoplifting
Management:
- sexual disinhibition
- gabapentin may be useful [1]
- sertraline 25-100 mg QD may reduce libido
- clomipramine 25-100 mg QD if obsessive behavior
- progesterone start 5 mg PO QD
- leuprolide 5-10 mg IM monthly if behavior improves with progesterone
General
sign/symptom
References
- Alkhalil C1, Tanvir F, Alkhalil B, Lowenthal DT.
Treatment of sexual disinhibition in dementia: case reports
and review of the literature.
Am J Ther. 2004 May-Jun;11(3):231-5.
PMID: 15133540
- Rosen T, Lachs MS, Pillemer K.
Sexual aggression between residents in nursing homes:
literature synthesis of an underrecognized problem.
J Am Geriatr Soc. 2010 Oct;58(10):1970-9. Review.
PMID: 20840462