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dirithromycin (Dynabac)
Tradename: Dynabac.
Indications:
- bacterial infections due to susceptible organisms
- pharyngitis, tonsillitis
- bronchitis, pneumonia
- skin or soft tissue infection [3]
Dosage: 500 mg PO QD for 7-14 days.
Tabs: 250 mg.
Antimicrobial activity:
Gram positive
- Streptococcus
- Streptococcus group A
- Streptococcus group B
- Streptococcus group C
- Streptococcus group G
- Streptococcus pneumonia
- Staphylococcus aureus (MSSA) (+/-)
- Staphylococcus epidermidis (+/-)
Gram negative
- Neisseria gonorrhoeae
- Moraxella catarrhalis
- Haemophilus influenzae (+/-)
- Legionella pneumophila [3]
Atypical bacteria
- Chlamydia species
- Mycoplasma pneumonia
Anaerobes
- Clostridium species (+/-)
Interactions
drug interactions
drug adverse effects of macrolide(s)
General
macrolide (macrolide antibiotic)
Properties
MISC-INFO: elimination route LIVER
pregnancy-category C
safety in lactation ?
Database Correlations
PUBCHEM correlations
References
- The Pharmacological Basis of Therapeutics, 9th ed.
Gilman et al, eds. Permagon Press/McGraw Hill, 1996
- Sanford Guide to antimicrobial therapy 1997
- Deprecated Reference