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dilute Russell viper venom time (dRVVT)
Indications:
1) suspected factor VII deficiency with prolonged PT, but normal aPTT & thrombin time; normal RVVT suggests factor VII deficiency
2) part of a screening panel for antiphospholipid antibodies; RVVT should be prolonged in the presence of antiphospho- lipid antibodies
Reference interval:
- 33-44 seconds [3]
Notes:
- Russell viper venom activates factor X directly.
General
Russell viper venom time (RVVT)
References
- Medical Knowledge Self Assessment Program (MKSAP) 11, American
College of Physicians, Philadelphia 1998
- Clinical Diagnosis & Management by Laboratory Methods,
19th edition, J.B. Henry (ed), W.B. Saunders Co.,
Philadelphia, PA. 1996, pg 736
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