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difelikefalin (Korsuva)
Indications:
- treatment of moderate-severe pruritus in adults undergoing hemodialysis
Dosage:
- 0.5. ug/kg IV bolus injection at the end of hemodialysis
- administer within 60 minutes of syringe preparation
Injection: 50 ug/mL
Adverse effects:
- diarrhea, dizziness, nausea, gait disturbances, falls, hyperkalemia, headache, somnolence, mental status change
Mechanism of action:
- kappa opioid receptor agonist
Interactions
drug adverse effects of opiates
General
opioid receptor agonist (narcotic)
References
- HIGHLIGHTS OF PRESCRIBING INFORMATION
KORSUVA