Search
diet soda
Indications:
- weight reduction
Adverse effects:
- diet soda consumption associated with in increased risk of stroke, myocardial infarction, cardiovascular mortality, all-cause dementia & Alzheimer's disease [2,4]
- increased mortality, mostly froma cardiovascular disease & cancer (RR=1.17) [3]
- artificial sweeteners (especially aspartame & acesulfame-K) are associated with increased cancer risk (RR=1.15 for aspartame) [4]
Clinical trials:
- people who drank diet soda while in a weight-loss program lost more weight than those who drank water [1] (Study funded by the American Beverage Association)
Related
artificial sweetener
General
carbonated beverage (soda, soft drink)
artificially-sweetened beverage
References
- Peters JC et al
The Effects of Water and Non-Nutritive Sweetened Beverages on
Weight Loss During a 12-week Weight Loss Treatment Program.
Obesity. May 26, 2014
PMID: 24862170
http://onlinelibrary.wiley.com/doi/10.1002/oby.20737/pdf
- Wersching H, Gardener H, Sacco RL
Sugar-Sweetened and Artificially Sweetened Beverages in Relation
to Stroke and Dementia. Are Soft Drinks Hard on the Brain?
Stroke April 20, 2017
PMID: 28428347
http://stroke.ahajournals.org/content/early/2017/04/20/STROKEAHA.116.016027
- Mullee A, Romaguera D, Pearson-Stuttard J et al.
Association between soft drink consumption and mortality in
10 European countries.
JAMA Intern Med 2019 Sept 3
PMID: 31479109
https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2749350
- Chazelas E et al.
Sugary drinks, artificially-sweetened beverages, and cardiovascular disease
in the NutriNet-Sante cohort.
J Am Coll Cardiol 2020 Nov 3; 76:2175.
PMID: 33121725
https://www.sciencedirect.com/science/article/abs/pii/S0735109720365967
- McGlynn ND, Khan KA, Wang L et al
Association of Low- and No-Calorie Sweetened Beverages as a Replacement
for Sugar-Sweetened Beverages With Body Weight and Cardiometabolic Risk.
A Systematic Review and Meta-analysis.
JAMA Netw Open. 2022;5(3):e222092.
PMID: 35285920 Free article
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2790045
- Debras C, Chazelas E, Srour B et al
Artificial sweeteners and cancer risk: Results from the NutriNet-Sante
population-based cohort study.
PLOS Medicine. 2022. Mar 24;19(3):e1003950
PMID: 35324894 PMCID: PMC8946744 Free PMC article
https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1003950