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dibucaine rectal (Nupercainal)
Tradename: Nupercainal.
Indications:
1) symptomatic relief of discomfort associated with hemorrhoids & perianal itching or irritation
2) relief of minor pains due to burns or irritation
Contraindications:
pregnancy-category ?
safety in lactation ?
Dosage:
1) apply 1% ointment or 0.5% cream every 12 hours, PRN or after bowel movement
2) 1 suppository PRN up to a max of 6/24 hours
3) burns/irritation:
a) apply to affected area
b) max dose 30 gm in 24 hours
Mechanism of action:
1) blocks Na+ channels
2) inhibition of neuronal impulses
Related
hemorrhoids (piles)
General
dibucaine
rectal agent
Database Correlations
PUBCHEM correlations
References
- The Pharmacological Basis of Therapeutics, 9th ed.
Gilman et al, eds. Permagon Press/McGraw Hill, 1996
- Drug Information & Medication Formulary, Veterans Affairs,
Central California Health Care System, 1st ed., Ravnan et al
eds, 1998